RegionsAir was a Part 121 regional airline. Its headquarters and maintenance base were located at the Smyrna Airport in Smyrna, Tennessee, USA|. The hub airports for RegionsAir were Lambert-St. Louis International Airport (STL) and Cleveland Hopkins International Airport (CLE). RegionsAir operated under a code-sharing agreement with TWA and American Airlines to provide flights to communities as AmericanConnection from Lambert-St. Louis International Airport, and as Continental Connection from Cleveland Hopkins International Airport. RegionsAir ceased all operations on March 8, 2007 and furloughed all of its employees a month later.